ETRB Antagonist 1

SKU: orb1685266

Description

This small molecule is a dual endothelin receptor antagonist, inhibiting binding to human ETA and ETB receptors with IC50 values of 268 nM and 1810 nM, respectively. It serves as a valuable research tool for investigating the endothelin system in cardiovascular and renal disease models, both in vitro and in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 290815-30-4
• MW: 483.93
• Purity: 99.71% (May vary between batches)
• Formula: C₂₂H₁₈ClN₅O₄S
• SMILES: COc1ccccc1Oc1c(Cl)nc(nc1NS(=O)(=O)c1ccc(C)cn1)-c1ccncc1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

N (6 chloro 5 (2 Methoxyphenoxy) 2 (pyridin 4 yl)pyriMidin 4 yl) 5 Methylpyridine 2 sulfonamide, N(6chloro5(2Methoxyphenoxy)2(pyridin4yl)pyriMidin4yl)5Methylpyridine2sulfonamide

Compound Identifiers

PubChem CID

11202530