ETP-45658

SKU: orb1305340

Description

ETP-45658

Research Area

Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 1198357-79-7
• MW: 311.34
• Purity: 99.14%
• Formula: C₁₆H₁₇N₅O₂
• SMILES: Cn1ncc2c(nc(nc12)-c1cccc(O)c1)N1CCOCC1
• Target: mTOR,DNA-PK,PI3K
• Solubility: DMSO:60 mg/mL (192.72 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.42 mM)

Bioactivity

• Target IC50:
  PI3Kβ:129.0 nM (IC50)|PI3Kα:22.0 nM (IC50)|DNA-PK:70.6 nM (IC50)|mTOR:152.0 nM (IC50)|PI3Kγ:717.3 nM (IC50)|PI3Kδ:39.8 nM (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Phosphoinositide 3-kinase, PI3k, PI3K, cancer, breast, DNA-PK, DNA-dependent protein kinase, DNAPK, ETP 45658, ETP45658, ETP-45658, Mammalian target of Rapamycin, Inhibitor, mTOR, inhibit

Compound Identifiers

PubChem CID

25229608