Ethylparaben

SKU: orb1310250

Description

Ethylparaben (Ethyl parahydroxybenzoate) is a standardized chemical allergen that acts by enhancing histamine release and cell-mediated immune responses. It is widely used in immunology and dermatology research to study allergic contact dermatitis mechanisms in both in vitro assays and in vivo models.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 120-47-8
• MW: 166.17
• Purity: 99.90% (May vary between batches)
• Formula: C₉H₁₀O₃
• SMILES: C(OCC)(=O)C1=CC=C(O)C=C1
• Target: Antibacterial,Antifungal
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (12.04 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:31 mg/mL (186.56 mM);DMSO:255 mg/mL (1534.57 mM)

Bioactivity

• In Vivo:
  In vivo studies indicate that ethylparaben has estrogenic effects in vivo in immature and ovariotectomized mice. A study on fetal exposure to ethylparaben revealed no changes in male anogenital distance and no changes of fetal testosterone production, but changes in gene expression levels pointed to subtle endocrine disrupting effects. A limited study in young male rats found no adverse effects, although tendencies to lower sperm counts are seen. Ethylparaben causes vitellogenin induction in fish.
• In Vitro:
  Ethylparaben has weak estrogenic and weak anti-androgenic effects in vitro.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, Antifungal, Inhibitor, Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate, Ethylparaben, inhibit

Compound Identifiers

PubChem CID

8434