Ethyl glucoside

SKU: orb1684094

Description

Ethyl β-D-glucopyranoside is a natural compound found in plants like Sisyrinchium palmifolium. It serves as a versatile enzymatic initiator for regioselective lactone polymerizations in vitro and is also studied as a shale inhibitor for drilling fluids.

Key Properties

• CAS Number: 3198-49-0
• MW: 208.209
• Purity: 99.68% (May vary between batches)
• Formula: C₈H₁₆O₆
• SMILES: CCO[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO
• Target: Others
• Solubility: DMSO:60 mg/mL (288.17 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.61 mM)

Bioactivity

• In Vivo:
  Metabonomic screening of human urine samples using 1H NMR spectroscopy has revealed the presence of signals resulting from the excretion of Ethyl glucoside. Experiments in volunteers have demonstrated that this Ethyl glucoside results from dietary exposure to the compound, which is present in beverages such as rice wine and sake, rather than representing a new route for the metabolism of ethanol by humans. The limited studies undertaken in volunteers indicate that Ethyl glucoside has a longer biological half life than ethanol itself. The potential problems associated with using this glucoside metabolite as a marker of ethanol consumption are considered.
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• In Vitro:
  EG exists as alpha (α) and beta (β) isomers. In this study, 0.48 μM of α-EG was found to increase the proliferation of normal human dermal fibroblasts (NHDF) by 121.0%, and the amount of collagen I produced by NHDF increased by 159.6% at an α-EG concentration of 0.048 μM, compared to those in cells cultured without α-EG. In NHDF cultured in α-EG-supplemented medium, the expression of fibroblast growth factor I and VII mRNA increased by 148.8 and 153.1%, at an α-EG concentration of 4.8 and 0.048 μM, respectively, as measured by a quantitative reverse transcription-polymerase chain reaction. Transcript levels of type I collagen genes, COL1A1 and COL1A2, increased by 152.4 and 129.7%, respectively, and that of a type III collagen gene, COL3A1, increased by 131.8% at an α-EG concentration of 0.48 μM.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

beta-D-Glucopyranoside, ethyl, b-D-Glucopyranoside, ethyl, Ethyl glucoside, Ethyl D-glucoside, β-D-Glucopyranoside, ethyl

Compound Identifiers

PubChem CID

11127487