ETHOTOIN

SKU: orb1745261

Description

Ethotoin (Peganone) is a hydantoin-based anticonvulsant compound, structurally related to phenytoin, used in epilepsy research. It is applied in both in vitro and in vivo studies to investigate mechanisms of seizure control and neuronal excitability.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 86-35-1
• MW: 204.23
• Purity: ≥98% (May vary between batches)
• Formula: C₁₁H₁₂N₂O₂
• SMILES: CCN1C(=O)NC(C1=O)C1=CC=CC=C1
• Target: Sodium Channel,Others

Bioactivity

• In Vivo:
  Administering Ethotoin via oral gavage at a dosage of 600 mg/kg to pregnant Sprague-Dawley CD rats on gestational day 18 resulted in a preweaning mortality rate of 2.0% and a 6.6% reduction in offspring weight compared to controls, indicating mild mortality and weight loss in the offspring .

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ETHOTOIN

Compound Identifiers

PubChem CID

3292