Ethisterone

SKU: orb1310743

Description

Ethisterone is a synthetic progestogen, specifically 17α-ethynyltestosterone, used in biochemical research. It serves as a reference compound in studies investigating progestogen receptor activity, steroid metabolism, and the historical development of synthetic hormones in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 434-03-7
• MW: 312.45
• Purity: 99.50% (May vary between batches)
• Formula: C₂₁H₂₈O₂
• SMILES: [H][C@@]12CC[C@@](O)(C#C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
• Target: Estrogen/progestogen Receptor,Estrogen Receptor/ERR
• Solubility: DMSO:3.53 mg/mL (11.3 mM)

Bioactivity

• In Vitro:
  In mice, daily administration of Ethisterone at doses ranging from 40 μg to 5 mg over a period of six days stimulates an increase in body weight.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Pregneninolone, progestogen Receptor, progestogenReceptor, steroidal, synthetic, Ethisterone, Estrogen Receptor/ERR, EstrogenReceptor, estrogen, Estrogen Receptor, ER, ERR, oral, inhibit, Inhibitor, 17a-Ethynyltestosterone, 17alpha-Ethynyltestosterone, 17α-Ethynyltestosterone, contraceptive

Compound Identifiers

PubChem CID

5284557