Ethacridine lactate

SKU: orb1220617

Description

Ethacridine lactate is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.(In Vitro):Acrinol is effective against S. aureus including MRSA, with the MICs ranging from 100-200 μg/mL. The MIC of Acrinol for Eschericia coli is 200-800 μg/mL, and it is over 1,600 μg/mL for Proteus vulgaris and Proteus mirabilis.(In Vivo):Ethacridine lactate can be used for termination of pregnancy.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1837-57-6
• MW: 343.38
• Purity: >98% (HPLC)
• Formula: C₁₈H₂₁N₃O₄
• SMILES: CC(O)C(O)=O.CCOc1ccc2nc3cc(N)ccc3c(N)c2c1
• Target: PARG
• Solubility: DMSO:100 mg/mL (291.22 mM)

Bioactivity

• In Vivo:
  Ethacridine lactate can be used for termination of pregnancy.
• In Vitro:
  Acrinol is effective against S. aureus including MRSA, with the MICs ranging from 100-200 μg/mL. The MIC of Acrinol for Eschericia coli is 200-800 μg/mL, and it is over 1, 600 μg/mL for Proteus vulgaris and Proteus mirabilis.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Acrinol | 69-DIAMINO-2-ETHOXYACRIDINE LACTATE

Quick Database Links

Gene Symbol

PARG