Esuprone

SKU: orb1700632

Description

Esuprone (LU-43839) is a reversible and selective monoamine oxidase A (MAO-A) inhibitor developed for depression research. Its anticonvulsant properties have been investigated in preclinical models, supporting its potential as a multifunctional therapeutic agent for neurological disorders.

Research Area

Metabolism Research, Neuroscience

Key Properties

• CAS Number: 91406-11-0
• MW: 282.31
• Purity: 99.66% (May vary between batches)
• Formula: C₁₃H₁₄O₅S
• SMILES: CC=1C=2C(=CC(OS(CC)(=O)=O)=CC2)OC(=O)C1C
• Target: MAO,Monoamine Oxidase
• Solubility: DMSO:2.83 mg/mL (10.02 mM)

Bioactivity

• Target IC50:
  MAO-A:7.3 nM
• In Vivo:
  Esuprone (800 mg; four volunteers) showed a rapid elimination with a half-life of about 4 h through plasma kinetics of esuprone.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Esuprone, MAO-A, LU 43839, LU43839, LU-43839

Compound Identifiers

PubChem CID

65827