Estramustine phosphate sodium

SKU: orb1302848

Description

Estramustine phosphate sodium is a small molecule antimicrotubule agent used in research to study prostate cancer. It induces G2/M phase cell cycle arrest and is employed in both in vitro and in vivo models to investigate mechanisms of cytotoxicity and drug resistance.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 52205-73-9
• MW: 564.35
• Purity: 96.44% (May vary between batches)
• Formula: C₂₃H₃₀Cl₂NNa₂O₆P
• SMILES: [Na+].[Na+].ClCCN(CCCl)C(=O)Oc3cc4CC[C@@H]1[C@H](CC[C@]2(C)[C@H](CC[C@@H]12)OP([O-])([O-])=O)c4cc3
• Target: Microtubule Associated,Apoptosis
• Solubility: DMSO:5.65 mg/mL (10.01 mM);H2O:62.5 mg/mL (110.75 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, Estramustine Phosphate, Estramustine phosphate, Estramustine phosphate disodium, Estramustine phosphate sodium, MiR-31, MicrotubuleAssociated, microtubule (MT) cytoskeleton, Microtubule/Tubulin, Microtubule Associated, inhibit, antitumour, antimitotic, Antimicrotubule, Apoptosis, prostate cancer, Ro 21-8837/001, transforming growth factor-β

Compound Identifiers

PubChem CID

444000