Estradiol Glow

SKU: orb533687

Description

Estradiol Glow is the ovarian steroid hormone 17-ß-Estradiol labeled with a novel low molecular weight orange/red fluorophor thus retain-ing its chemical properties and it´s biological activity. This allows for a wide range of applications including: analysis of in vivo andin vitro steroid uptake in real time; monitoring of intracellular and subcellular steroid transport; studies on steroid-binding proteins; use as tracer for steroid immunoassays (to replace isotopes or enzymes; photodynamic elimination of estrogen sensitive tissues and cells in experimental settings with possible future clinical im-plications Estradiol Glow can be histologically fixed using formaldehyde or glutaraldehyde without any significant loss of fluorescence intensity. Typical concentration range used for cell culture experiments: 10-5M-10-7M (may vary depending on cell line and individual experimental set-up).

Research Area

Cancer Biology; Pharmacology & Drug Discovery

Images & Validation

• Application Notes:
  Spectroscopic Propertie: λexc 467 nm, λem 618 nm, ε 29.0 L mmol-1 cm-1(PBS pH 7.4), λexc 501 nm, λem 596 nm, ε 52.0 L mmol-1 cm-1(ethanol).

Key Properties

• MW: Theoretical MW: 771.95 g/mol
• Purity: > 97% (DC, NMR)
• Formula: C₄₇H₆₇BrN₂O₂
• SMILES: c1c(ccc(c1)/C=C/c1cc[n+](cc1)CCCCCCCCOc1ccc2c(c1)CCC1C2CC[C@@]2([C@H](CCC12)O)C)N(CCCC)CCCC.Br

Storage & Handling

• Storage: store at 4 °C
• Form/Appearance: lyophilised, glassy to waxy appearance; Color: brownish-red
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Fluorescently labeled Estradiol

Compound Identifiers

PubChem CID

176418048