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Esomeprazole

SKU: orb1306590

Description

Esomeprazole, the S-isomer of omeprazole, is a proton pump inhibitor that also acts as a selective inhibitor of the lysosomal cysteine protease legumain. This dual activity makes it a research tool for investigating mechanisms of cancer metastasis in both cellular and animal models.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Images & Validation

Key Properties

CAS Number119141-88-7
MW345.416
Purity98.20% (May vary between batches)
FormulaC17H19N3O3S
SMILESCOC1=CC2=C(C=C1)N=C(N2)[S@@](=O)CC1=NC=C(C)C(OC)=C1C
TargetProton pump,Antibacterial,Cysteine Protease
SolubilityDMSO:1 mg/mL (2.9 mM)

Bioactivity

In Vivo
In an orthotopic transplantation nude mouse model, Esomeprazole reduced lung metastasis of MDA-MB-231 breast cancer cells.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

lysosomal cysteine protease, K+-ATPase, inhibit, Esomeprazole, fibrosis, Inhibitor, gastroesophageal, CYP3A4, Cysteine Protease, CysteineProtease, (S)-Omeprazole, antacid, anti-inflammation, Proton pump, Proton Pump, Protonpump

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

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50 mg
$ 80.00
100 mg
$ 100.00
500 mg
$ 170.00
DispatchUsually dispatched within 5-10 working days
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