Eslicarbazepine Acetate

SKU: orb1225562

Description

Eslicarbazepine acetate is an antiepileptic drug. (In Vivo):Eslicarbazepine acetate is an antiepileptic drug. It is a prodrug which is activated to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine. Eslicarbazepine acetate is a prodrug for (S)-(+)-licarbazepine, the major active metabolite of oxcarbazepine. Its mechanism of action is therefore identical to that of oxcarbazepine. Eslicarbazepine acetate may not produce as high peak levels of (S)-(+)-licarbazepine immediately after dosing as does oxcarbazepine which could theoretically improve tolerability.

Key Properties

• CAS Number: 236395-14-5
• MW: 296.324
• Purity: >98% (HPLC)
• Formula: C₁₇H₁₆N₂O₃
• SMILES: O=C(N1C2=CC=CC=C2C[C@H](OC(C)=O)C3=CC=CC=C31)N
• Target: Others
• Solubility: DMSO: 59 mg/mL (199.1 mM)/Ethanol: 11 mg/mL (37.12 mM)

Bioactivity

• In Vivo:
  Eslicarbazepine acetate is an antiepileptic drug. It is a prodrug which is activated to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine. Eslicarbazepine acetate is a prodrug for (S)-(+)-licarbazepine, the major active metabolite of oxcarbazepine. Its mechanism of action is therefore identical to that of oxcarbazepine. Eslicarbazepine acetate may not produce as high peak levels of (S)-(+)-licarbazepine immediately after dosing as does oxcarbazepine which could theoretically improve tolerability.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BIA 2-093

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