Escin IIB

SKU: orb1684617

Description

Escin IIB, a natural saponin from horse chestnut seeds, demonstrates potent anti-inflammatory and gastroprotective activities in preclinical models. It is utilized in research on inflammatory pathways and gastric mucosal defense, with applications in both in vivo and in vitro experimental studies.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 158800-83-0
• MW: 1101.24
• Purity: 99.48% (May vary between batches)
• Formula: C₅₄H₈₄O₂₃
• SMILES: [H][C@@]12CC(C)(C)[C@@H](OC(=O)C(\C)=C/C)[C@H](OC(C)=O)[C@]1(CO)[C@H](O)C[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O[C@@H]4O[C@@H]([C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O[C@@H]4OC[C@@H](O)[C@H](O)[C@H]4O)C(O)=O)[C@](C)(CO)[C@]3([H])CC[C@@]12C
• Target: Immunology/Inflammation related

Bioactivity

• In Vivo:
  Escin IIB (10-50 mg/kg, p.o.) can effectively inhibit ethanol-induced gastric mucosal injury in rats.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Aescin IIB, NO Synthase, NOS

Compound Identifiers

PubChem CID

10260627