Erythromycin ethylsuccinate

SKU: orb1310577

Description

Erythromycin ethylsuccinate (EES) is a semisynthetic macrolide antibiotic derived from Streptomyces erythreus. It is widely used in research for studying antibacterial mechanisms and efficacy in both in vitro susceptibility assays and in vivo infection models.

Research Area

Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 1264-62-6
• MW: 862.05
• Purity: 98.00% (May vary between batches)
• Formula: C₄₃H₇₅NO₁₆
• SMILES: CCOC(=O)CCC(=O)O[C@H]1[C@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)O[C@H](C)C[C@@H]1N(C)C
• Target: Antibiotic,HIV Protease,Antibacterial,ribosome,Autophagy
• Solubility: DMSO:158 mg/mL (183.28 mM);Ethanol:158 mg/mL (183.28 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (4.64 mM)

Bioactivity

• In Vitro:
  It inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

50S ribosome, Bacterial, Autophagy, Antibiotic, EES, Erythromycin ethyl, Erythromycin ethylsuccinate, Inhibitor, Human immunodeficiency virus, HIV, HIV Protease, HIVProtease, inhibit

Compound Identifiers

PubChem CID

443953