Ertugliflozin L-pyroglutamic acid

SKU: orb1940725

Description

Ertugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatment of type 2 diabetes mellitus.(In Vitro):Ertugliflozin L-pyroglutamic acid demonstrated >2000-fold selectivity for SGLT2 over SGLT.(In Vivo):The oral administration of Ertugliflozin L-pyroglutamic to rats acid showed concentration-dependent glucosuria.

Key Properties

• CAS Number: 1210344-83-4
• MW: 566
• Purity: >98% (HPLC)
• Formula: C₂₇H₃₂ClNO₁₀
• SMILES: OC(=O)[C@@H]1CCC(=O)N1.CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1
• Target: Caspase-3
• Solubility: In Vitro: DMSO : ≥ 125 mg/mL (220.85 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PF-04971729 L-pyroglutamic acid

Quick Database Links

Gene Symbol

Caspase-3