Erteberel

SKU: orb1300884

Description

Erteberel (LY500307) is a highly selective estrogen receptor β (ERβ) agonist, exhibiting an EC50 of 0.66 nM and 32-fold selectivity over ERα. This research compound is used in vitro and in vivo to study ERβ's role in neurological, inflammatory, and metabolic processes.

Research Area

Metabolism Research

Key Properties

• CAS Number: 533884-09-2
• MW: 282.33
• Purity: 99.87%
• Formula: C₁₈H₁₈O₃
• SMILES: [H][C@]12CCC[C@@]1([H])c1cc(O)ccc1O[C@H]2c1ccc(O)cc1
• Target: Estrogen/progestogen Receptor,Estrogen Receptor/ERR
• Solubility: DMSO:57 mg/mL (201.89 mM);Ethanol:57 mg/mL (201.89 mM);H2O:<1 mg/mL

Bioactivity

• Target IC50:
  ERRβ:0.66 nM (EC50)|ERβ:1.54 nM (Ki)|ERβ:3.61 nM (EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

progestogenReceptor, progestogen Receptor, LY500307, LY-500307, LY 500307, Inhibitor, inhibit, Estrogen Receptor, Estrogen Receptor/ERR, EstrogenReceptor, ERR, ERβ, Erteberel

Compound Identifiers

PubChem CID

10286159