ERRγ-IN-1

SKU: orb3210884

Description

ERRγ-IN-1 is an inhibitor of ERRγ with an IC50 value of 0.04 μM. It activates MAPK (p44/p42) and suppresses ERRγ activity. ERRγ-IN-1 significantly enhances iodine uptake in anaplastic thyroid cancer xenografts and inhibits tumor growth in nude mice. It is applicable for research in anaplastic thyroid cancer.

Key Properties

• CAS Number: 2170732-60-0
• MW: 456.62
• Formula: C₃₀H₃₆N₂O₂
• SMILES: C(=C(/CCCO)\C1=CC=CC=C1)(\C2=CC=C(C=C2)N3CCN(C(C)C)CC3)/C4=CC=C(O)C=C4
• Target: Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Estrogen Receptor/ERR