Eriodictyol-7-O-glucoside

SKU: orb1684619

Description

Eriodictyol-7-O-glucoside is a flavonoid antioxidant that scavenges free radicals and activates the Nrf2 pathway. This mechanism confers protective effects against cisplatin-induced cytotoxicity, as demonstrated in cellular studies, supporting its research in chemoprotection and oxidative stress models.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 38965-51-4
• MW: 450.39
• Purity: 99.99% (May vary between batches)
• Formula: C₂₁H₂₂O₁₁
• SMILES: OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C[C@H](Oc3c2)c2ccc(O)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O
• Target: Nrf2

Bioactivity

• In Vitro:
  Eriodictyol-7-O-glucoside was able to stabilize Nrf2 by delaying Nrf2 degradation, resulting in the accumulation of Nrf2 protein and activation of the Nrf2-dependent protective response. Cotreatment of HRMC cells with Eriodictyol-7-O-glucoside significantly improved cell survival under cisplatin exposure.

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cisplatin, Keap1-Nrf2, Nrf2, inhibit, Eriodictyol7Oglucoside, Eriodictyol-7-O-glucoside, Eriodictyol 7 O glucoside, flavonoid, Inhibitor, radical, scavenger

Compound Identifiers

PubChem CID

13254473