Ergosterol peroxide

SKU: orb1685020

Description

Ergosterol peroxide is a fungal-derived sterol with demonstrated anti-tumor, anti-inflammatory, and antioxidant properties. It has shown pro-apoptotic and anti-proliferative effects in vitro and exhibits activity against mycobacteria and parasites in research models.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 2061-64-5
• MW: 428.65
• Purity: 98.43% (May vary between batches)
• Formula: C₂₈H₄₄O₃
• SMILES: C[C@@]12[C@@]3([C@@]4([C@]5([C@](C)(CC3)[C@@]([C@@H](/C=C/[C@@H](C(C)C)C)C)(CC5)[H])[H])C=C[C@@]1(OO4)C[C@@H](O)CC2)[H]
• Target: Antibacterial
• Solubility: DMSO:3.12 mg/mL (7.28 mM);Methanol:12.5 mg/mL (29.16 mM)

Bioactivity

• Target IC50:
  T. cruzi:6.74 µg/mL
• In Vitro:
  Ergosterol peroxide showed an IC50 of 6.74 µg/mL against T. cruzi, but did not lyse erythrocytes even at concentrations as high as 1600 µg/mL and had no toxic effects on mammalian cells. In vitro experiments showed that Ergosterol peroxide exhibited significant lysogenic activity when interacting with Trypanosoma cruzi, possibly due to rupture of the parasite cell membrane.

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

beta-catenin, betacatenin, CDK, Akt, Antifection, bcatenin, NSC31324, NSC 31324, JAK, JNK, ERK, STAT, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, p38 MAPK, p38MAPK, VEGFR, βcatenin, TGF-β/Smad

Compound Identifiers

PubChem CID

5351516