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ERβ agonist-2

SKU: orb3211398

Description

ERβagonist-2 (Page 72) is a selective ERβ agonist with an EC50 of 800 nM or less. This compound specifically inhibits the activation and/or proliferation of T cells, thereby reducing circulating T cell levels in subjects, without significantly affecting levels of circulating neutrophils, monocytes, or B cells. ERβagonist-2 is applicable in research on chronic heart failure post-myocardial infarction, graft-versus-host disease, multiple sclerosis, and experimental autoimmune encephalomyelitis.

Images & Validation

Key Properties

CAS Number628321-25-5
MW304.34
FormulaC19H16N2O2
SMILESOC1=CC=C(C=C1)C=2C=3C=CC=CC3NC2C=4C(=NOC4C)C
TargetEstrogen Receptor/ERR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information