Equol (R,S)

SKU: orb1303344

Description

(±)-Equol is a non-steroidal estrogen metabolite of daidzein with selective affinity for ERβ over ERα. Its (S)-enantiomer acts as a potent ER agonist, while the racemate also functions as a dihydrotestosterone antagonist. This dual activity makes it a valuable research tool for studying hormone-dependent cancers and endocrine pathways in vitro and in vivo.

Research Area

Metabolism Research

Key Properties

• CAS Number: 94105-90-5
• MW: 242.27
• Purity: >98%
• Formula: C₁₅H₁₄O₃
• SMILES: OC=1C=C2C(CC(CO2)C3=CC=C(O)C=C3)=CC1
• Target: Transcription factor
• Solubility: DMSO:100 mg/mL (412.76 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (16.51 mM)

Bioactivity

• Target IC50:
  ERα:6.41 nM(Ki)|ERβ:0.73 nM(Ki)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, ERα, ERβ, ERR, Equol, Estrogen Receptor/ERR, EstrogenReceptor, Estrogen Receptor, Inhibitor, DrugMetabolite, Drug Metabolite, (R,S)-Equol, (±)Equol, (±)-Equol, (±) Equol, 66036-38-2, progestogen Receptor, progestogenReceptor

Compound Identifiers

PubChem CID

382975