EPZ032597

SKU: orb1739393

Description

EPZ032597 is a potent and selective SMYD2 inhibitor (IC50 = 16 nM) with demonstrated anticancer activity. Research indicates its utility in studying epigenetic mechanisms in oncology, showing efficacy in preclinical models of pancreatic cancer, including in vitro cell studies and in vivo tumor growth inhibition.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 1887193-58-9
• MW: 377.44
• Purity: 99.97% (May vary between batches)
• Formula: C₂₀H₂₃N₇O
• SMILES: C(NC1CN(CC2=CN(CC3=CC=CC=C3)N=C2)C1)(=O)C4=CN(N=N4)C5CC5
• Target: Histone Methyltransferase
• Solubility: DMSO:55 mg/mL (145.72 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EPZ032597, EPZ-032597, EPZ 032597, Grp94-IN2, Grp94 IN 2, Grp94 IN-2, Grp94-IN 2, Grp94IN2, Histone Methyltransferase, HistoneMethyltransferase, SMYD2

Compound Identifiers

PubChem CID

132220034