Epofolate

SKU: orb1741249

Description

BMS753493 is a folate receptor-targeted prodrug of epothilone, delivering its antimitotic payload into cancer cells overexpressing this receptor. Upon internalization, it stabilizes microtubules, inhibiting cell division. This targeted mechanism has been investigated in preclinical in vitro and in vivo models for various solid tumors.

Research Area

Cell Biology

Key Properties

• CAS Number: 958646-17-8
• MW: 1569.74
• Formula: C₆₇H₉₂N₁₆O₂₂S₃
• SMILES: C(COC(OCCSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CC[C@H](NC(=O)C1=CC=C(NCC=2N=C3C(NC2)=NC(N)=NC3=O)C=C1)C(O)=O)=O)CC(O)=O)=O)CCCNC(=N)N)=O)CC(O)=O)=O)C(O)=O)=O)N4[C@@]5([C@]4(CCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O[C@H](\C(=C\C=6N=C(C)SC6)\C)C5)[H])[H]
• Target: Apoptosis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135566069