Epitinib succinate

SKU: orb1694205

Description

Epitinib succinate (HMPL-813 succinate) is an orally bioavailable, brain-penetrant EGFR inhibitor used in cancer research. It is employed in both in vitro and in vivo studies to investigate its potential therapeutic effects against EGFR-driven malignancies, including those affecting the central nervous system.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2252334-12-4
• MW: 548.59
• Purity: 99.79%
• Formula: C₂₈H₃₂N₆O₆
• SMILES: OC(=O)CCC(O)=O.CCN1CCN(CC1)C(=O)Nc1cc2c(Nc3cccc(c3)C#C)ncnc2cc1OC
• Target: EGFR
• Solubility: DMSO:1 mg/mL (1.82 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.82 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EGFR, Epitinib succinate, Epitinib Succinate, HMPL 813 Succinate, HMPL813 Succinate, HMPL-813 succinate, HMPL-813 Succinate

Compound Identifiers

PubChem CID

135379897