Epidermal mitosis inhibiting pentapeptide

SKU: orb3180460

Description

Epidermalmitosisinhibiting pentapeptide, a pentapeptide, acts as a physiological inhibitor of epidermal cell proliferation. It notably reduces the DNA synthesis rate and mitotic rate of epidermal keratinocytes. In skin cancer models, it moderately enhances tumor formation but shows a stronger tendency to promote the regression of established tumors. It can be hydrolyzed by angiotensin-converting enzyme (ACE) and is applicable in cancer process research.

Key Properties

• Target: DNA/RNA Synthesis
• CAS Number: 106678-69-7
• MW: 517.45
• Formula: C₁₉H₂₇N₅O₁₂
• SMILES: [C@H](C(N[C@H](C(NCC(O)=O)=O)CO)=O)(NC([C@@H](NC(=O)[C@@H]1CCC(=O)N1)CCC(O)=O)=O)CC(O)=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA/RNA Synthesis