Epibrassinolide

SKU: orb1301730

Description

Epibrassinolide

Research Area

Cell Biology

Key Properties

• CAS Number: 78821-43-9
• MW: 480.68
• Purity: 98.35%
• Formula: C₂₈H₄₈O₆
• SMILES: CC(C)[C@@H](C)[C@@H](O)[C@H](O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3COC(=O)[C@H]4C[C@H](O)[C@H](O)C[C@]4(C)[C@H]3CC[C@]12C
• Target: Apoptosis
• Solubility: DMSO:48.1 mg/mL (100.07 mM)

Bioactivity

• In Vitro:
  Epibrassinolide(EBR) was shown as a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth.It has been shown to protect neuronal PC12 cells from 1-methyl-4-phenylpyridinium-induced oxidative stress and consequent apoptosis in dopaminergic neurons
• Cell Research:
  Cells were seeded at 1*10^4 density per well in 96-well plates and exposed to various concentrations of EBR for 24 and 48 h. 10 ul 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) dye (5 mg/ml) was added to each well and cells were kept at 37 C for 4 h. The resulting formazan crystals were solubilized in 200 ul DMSO. The density of the solubilized formazan was read at 570 nm spectrophotometrically.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis inducer, B1105, B-1105, B 1105, Apoptosis, BP 55, BP55, BP-55, 24-Epibrassinolide, Epibrassinolide

Compound Identifiers

PubChem CID

443055