Epalrestat

SKU: orb1308563

Description

Epalrestat (ONO-2235) is a well-tolerated aldose reductase inhibitor for long-term research use. It effectively alleviates symptoms and slows the progression of diabetic neuropathy in preclinical models, particularly under conditions of good glycemic control. Its application extends to in vitro enzyme assays and in vivo studies of diabetic complications.

Research Area

Metabolism Research

Key Properties

• CAS Number: 82159-09-9
• MW: 319.4
• Purity: 99.54% (May vary between batches)
• Formula: C₁₅H₁₃NO₃S₂
• SMILES: CC(=C/C1=CC=CC=C1)\C=C1/SC(=S)N(CC(O)=O)C1=O
• Target: Reductase
• Solubility: 10% DMSO+90% Corn Oil:0.5 mg/mL (1.57 mM);DMSO:23.18 mg/mL (72.57 mM)

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Epalrestat, Inhibitor, inhibit, ONO2235, ONO-2235, ONO 2235, Aldose Reductase, Aldose reductase

Compound Identifiers

PubChem CID

1549120