Ep300/CREBBP-IN-3

SKU: orb1983354

Description

Ep300/CREBBP-IN-3 (Example 61) is a dual inhibitor of the histone acetyltransferases EP300 and CREBBP with IC50 values of 56 nM and 95 nM, respectively. This cell-permeable compound is a valuable chemical probe for epigenetic and cancer research, enabling mechanistic studies in both cellular and biochemical assays.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2259641-47-7
• MW: 531.50
• Formula: C₂₆H₂₅F₄N₅O₃
• SMILES: F[C@@H]1C[C@@H](N(C1)C(=O)C1(CCCCC1)c1ccc(cc1)C(=O)C(F)(F)F)C(=O)Nc1ccc2[nH]ncc2n1
• Target: Others,Histone Acetyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

142504215