EP3 antagonist 6

SKU: orb2566309

Description

Compound 5 is a potent, selective, and orally bioavailable EP3 receptor antagonist with a 1.9 nM IC50. It is a valuable research tool for studying prostaglandin E2 signaling in models of preterm labor, as demonstrated by its inhibition of PGE2-induced uterine contractions in pregnant rats.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 499149-94-9
• SMILES: C(N[C@H](CC(C)C)C1=CC(C)=CC(C)=C1)(=O)C2=C(CCC(O)=O)C=CC(COC3=C(C)C=CC=C3)=C2
• Target: Prostaglandin Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46887059