Entasobulin

SKU: orb1308333

Description

Entasobulin is a small molecule that disrupts microtubule assembly by inhibiting β-tubulin polymerization. This mechanism confers potential anticancer properties, supporting its use in both in vitro cell-based assays and in vivo tumor model studies for cancer research.

Research Area

Signal Transduction

Key Properties

• CAS Number: 501921-61-5
• MW: 439.89
• Purity: >99.99% (May vary between batches)
• Formula: C₂₆H₁₈ClN₃O₂
• SMILES: Clc1ccc(Cn2cc(C(=O)C(=O)Nc3ccc4ncccc4c3)c3ccccc23)cc1
• Target: Microtubule Associated
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (7.5 mM);DMSO:155 mg/mL (352.36 mM)

Bioactivity

• In Vitro:
  Entasobulin is an indolizine-glyoxylamide based small molecule. It shows substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, MicrotubuleAssociated, Microtubule Associated, Microtubule/Tubulin, Inhibitor, Entasobulin, β-tubulin polymerization, Tubulin β

Compound Identifiers

PubChem CID

10203597