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Entacapone

SKU: orb1306079

Description

Entacapone

Research Area

Cell Biology, Neuroscience

Images & Validation

Key Properties

CAS Number130929-57-6
MW305.29
Purity>98%
FormulaC14H15N3O5
SMILESCCN(CC)C(=O)C(=C/c1cc(O)c(O)c(c1)[N+]([O-])=O)\C#N
TargetMethyltransferase
SolubilitySoluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 3 mg/ml).

Bioactivity

Target IC50
COMT:151 nM
In Vivo
In various tissues, such as the liver, duodenum, kidney, and lung, Entacapone inhibits the activity of catechol-O-methyltransferase (COMT). Additionally, in PC12 cells, Entacapone can suppress extracellular cytotoxicity induced by the aggregation of α-syn and β-amyloid (Aβ).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

COMT, ?FTO?knockdown, 116314-67-1, inhibit, OR611, OR-611, OR 611, Parkinson's disease, metabolic disorder, Inhibitor, Entacapone

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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10 mg
$ 160.00
50 mg
$ 240.00
DispatchUsually dispatched within 5-10 working days
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