ENPP1 Inhibitor C

SKU: orb3027332

Description

ENPP1 Inhibitor C is a small molecule that selectively inhibits ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1). It is a research tool for studying cancer immunology and metastasis, particularly in triple-negative breast cancer models, with utility in both in vitro enzymatic assays and in vivo tumor studies.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2378640-92-5
• MW: 282.34
• Purity: 99.28% (May vary between batches)
• Formula: C₁₅H₁₈N₆
• SMILES: N=1C=NN2C1N=C(C(=C2N(C)C)CC=3C=CC=C(N)C3)C
• Target: PDE
• Solubility: DMSO:80 mg/mL (283.35 mM);Ethanol:10 mg/mL (35.42 mM);DMF:10 mg/mL (35.42 mM)

Bioactivity

• Target IC50:
  ENPP1 (pNP-TMP assays):0.48 μM|ENPP1 (ATP assays):2.0 μM|ENPP1 (TG-mAMP assays):0.26 μM
• In Vitro:
  ENPP1 Inhibitor C is a potent inhibitor of ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) with IC50 values of 0.26 μM, 0.48 μM, and 2.0 μM as assessed using TG-mAMP, pNP-TMP, and ATP assays, respectively.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ENPP1 Inhibitor C, ENPP-1 Inhibitor C, Enpp-1-IN-2, PDE1

Quick Database Links

Gene Symbol

PDE