Enpp-1-IN-30

SKU: orb3211471

Description

Enpp-1-IN-30 (compound 44a) is an ENPP1 inhibitor with oral bioavailability and a human IC50 of 13.1 nM. It prevents cGAMP degradation and activates the STING pathway. Enpp-1-IN-30 induces cytokine release to enhance the innate immune response and demonstrates antitumor efficacy in syngeneic mouse models. This compound is applicable for colon cancer research.

Key Properties

• Target: PDE

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PDE