Endothelial lipase inhibitor-1

SKU: orb1309704

Description

This compound is a potent and selective endothelial lipase inhibitor, exhibiting an IC50 of 49 nM. It serves as a valuable research tool for studying lipid metabolism, atherosclerosis, and inflammation in both cellular assays and animal models.

Research Area

Cardiovascular Research; Metabolism Research; Pharmacology & Drug Discovery, Metabolism Research

Key Properties

• CAS Number: 1466427-02-0
• MW: 406.43
• Purity: 97.38% (May vary between batches)
• Formula: C₂₂H₂₂N₄O₄
• SMILES: Nc1c([nH]c(=O)[nH]c1=O)C(=O)N[C@@H]1CCCc2c(OCc3ccccc3)cccc12
• Target: Lipase
• Solubility: DMSO:40 mg/mL (98.42 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.92 mM)

Bioactivity

• Target IC50:
  Endothelial lipase:49 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Endothelial lipase inhibitor1, Endothelial lipase inhibitor-1, Endothelial lipase, Endothelial lipase inhibitor 1

Compound Identifiers

PubChem CID

117926774