Endosidin5(ES5)

SKU: orb2279913

Description

Endosidine 5 (ES5), is one of the most potent small molecules interferes with recycling endosomes through Annexin A6, thereby promoting the release and expression of mRNA into the cytoplasm. The delivered mRNAs is greatly enhanced via inhibition of endocytic recycling in cells and in live mice. NAV2729 (NAV) and endosidin 5 (ES5), resulted in significant enhancement (1.5–2 folds) of LNP-mediated delivery of Fluc mRNAs. Incubation of NAV and ES5 together caused modest further increases in Fluc expression in comparison to the sole application of either compound.

Key Properties

• CAS Number: 491585-87-6
• MW: 314
• Purity: 0.98
• Formula: C₂₀H₁₈N₄

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only