Endomorphin-1

• Catalog Number: orb2693577
• Category: Proteins
• Description: Endomorphin-1 (EM-1) (amino acid sequence Tyr-Pro-Trp-Phe-NH2) is an endogenous opioid peptide and one of the two endomorphins. It is a high affinity, highly selective agonist of the μ-opioid receptor, and along with endomorphin-2 (EM-2), has been proposed to be the actual endogenous ligand of the μ-receptor. EM-1 produces analgesia in animals and is equipotent with morphine in this regard. The gene encoding for EM-1 has not yet been identified,[4] and it has been suggested that endomorphins could be synthesized by an enzymatic, non-ribosomal mechanism.
• Target: Opioid Receptor
• Purity: ≥95%
• Protein Sequence: YPWF-NH2
• MW: 610.72
• Solubility (25°C): Water: 25 mg/mL. DMSO: ≥ 50 mg/mL
• CAS Number: 189388-22-5
• Formula: C₃₄H₃₈N₆O₅
• Note: For research use only