EN171

SKU: orb2665230

Description

EN171 is a covalent molecular glue that selectively targets 14-3-3 proteins, enhancing their interactions with client proteins like ERα, YAP, and TAZ to disrupt oncogenic transcriptional pathways. It also serves as a recruiter in heterobifunctional molecules for the cytosolic sequestration of nuclear targets such as BRD4, applicable in cancer research and targeted protein degradation studies.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2191110-79-7
• MW: 270.37
• Formula: C₁₇H₂₂N₂O
• SMILES: O=C(C=C)N1CCC2(C1)CN(CC=3C=CC=CC3)CC2
• Target: Molecular Glues,Others,Hippo pathway,Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132317810