Emavusertib Tosylate

SKU: orb2814951

Description

Emavusertib Tosylate (CA-4948) is a selective IRAK4/FLT3 inhibitor with potent antitumor activity in preclinical models. It demonstrates strong cellular efficacy in ABC DLBCL and AML cell lines and achieves significant tumor growth inhibition in vivo, supported by favorable oral pharmacokinetics.

Research Area

Cardiovascular Research, Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 2376399-41-4
• MW: 663.7
• Formula: C₃₁H₃₃N₇O₈S
• SMILES: S(=O)(=O)(O)C1=CC=C(C)C=C1.N(C(=O)C=1N=C(OC1)C=2C=C(C)N=CC2)C3=C(N=C4C(=C3)OC(=N4)N5CCOCC5)N6CC[C@@H](O)C6
• Target: IRAK,MyD88,Apoptosis,NF-κB,FLT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

167713303