Emavusertib Mesylate

SKU: orb2814948

Description

Emavusertib Mesylate (CA-4948) is a selective IRAK4/FLT3 inhibitor with potent antitumor activity in ABC DLBCL and AML models. It demonstrates high oral bioavailability and achieves >90% tumor growth inhibition in vivo, correlating with strong pharmacodynamic modulation.

Research Area

Cardiovascular Research, Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 2376399-40-3
• MW: 587.61
• Formula: C₂₅H₂₉N₇O₈S
• SMILES: S(C)(=O)(=O)O.N(C(=O)C=1N=C(OC1)C=2C=C(C)N=CC2)C3=C(N=C4C(=C3)OC(=N4)N5CCOCC5)N6CC[C@@H](O)C6
• Target: NF-κB,Apoptosis,IRAK,FLT,MyD88

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

167713308