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Eltrombopag Olamine
Catalog Number: orb1300431
| Catalog Number | orb1300431 |
|---|---|
| Category | Small Molecules |
| Description | Eltrombopag Olamine |
| Purity | 99.87% |
| MW | 564.63 |
| Biological Activity | Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. |
| CAS Number | [496775-62-3] |
| Formula | C29H36N6O6 |
| SMILES | NCCO.NCCO.CC1=NN(C(=O)\C1=N/Nc1cccc(-c2cccc(c2)C(O)=O)c1O)c1ccc(C)c(C)c1 |
| Storage | -20°C |
| Note | For research use only |
Eltrombopag Olamine [orb1222171]
> 98% (HPLC)
496775-62-3
564.6
C29H36N6O6
2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg, 1 g, 500 mg
