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Catalog Number | orb1300431 |
---|---|
Category | Small Molecules |
Description | Eltrombopag Olamine |
CAS Number | 496775-62-3 |
Purity | 99.94% |
MW | 564.63 |
SMILES | NCCO.NCCO.CC1=NN(C(=O)C\1=N/Nc1cccc(-c2cccc(c2)C(O)=O)c1O)c1ccc(C)c(C)c1 |
Formula | C29H36N6O6 |
Biological Activity | Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
496775-62-3 |
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