Eltoprazine dihydrochloride

SKU: orb1299542

Description

Eltoprazine dihydrochloride is a small molecule originally developed for aggression. Recent research investigates its application in Parkinson's disease, specifically for reducing L-DOPA-induced dyskinesias, as evidenced by studies in both animal models and dyskinetic patients.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 143485-51-2
• MW: 293.19
• Purity: 99.94%
• Formula: C₁₂H₁₈Cl₂N₂O₂
• SMILES: Cl.Cl.c1cc2c(c(N3CCNCC3)c1)OCCO2
• Target: 5-HT Receptor,Others
• Solubility: DMSO:10 mg/mL (34.11 mM)

Bioactivity

• In Vitro:
  In the elevated plus maze eltoprazine increased anxiety like behavior. On the other hand, it induced a clear cut anxiolytic effect in context fear conditioning test starting at ca. 0.3 mg/kg

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Eltoprazine, Eltoprazine Dihydrochloride, Eltoprazine dihydrochloride

Compound Identifiers

PubChem CID

67857432