ElteN378

SKU: orb1685185

Description

ElteN378 is a potent, low molecular weight synthetic inhibitor of FKBP12, exhibiting sub-nanomolar affinity (Ki = 0.5 nM) comparable to rapamycin. It serves as a valuable chemical probe for studying FKBP12 function and mTOR signaling pathways in both cellular and animal models of immunology and cancer research.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 1421366-99-5
• MW: 378.46
• Purity: 99.06% (May vary between batches)
• Formula: C₂₃H₂₆N₂O₃
• SMILES: C(C(=O)C1=CC=CC=C1)(=O)N2[C@H](C(NCCCC3=CC=CC=C3)=O)CCCC2
• Target: FKBP,mTOR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.64 mM);DMSO:10 mg/mL (26.42 mM)

Storage & Handling

• Storage: Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

mTOR (FKBP12), ElteN 378, ElteN378, ElteN-378

Compound Identifiers

PubChem CID

71563275