Eltanexor Z-isomer

SKU: orb1709330

Description

The Z-isomer of Eltanexor is the less active form of the CRM1 inhibitor KPT-8602. It demonstrates variable potency in vitro, with IC50 values ranging from <100 nM in MM1.S cells to >30 µM in 3T3 fibroblasts. This selective inhibitor is used in cancer research, particularly for studying hematological malignancies in cellular models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1642300-78-4
• MW: 428.29
• Formula: C₁₇H₁₀F₆N₆O
• SMILES: NC(=O)C(=C/n1cnc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)\c1cncnc1
• Target: CRM1,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

117763569