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Ellipticine

SKU: orb1309545

Description

Ellipticine is a potent antineoplastic agent with multiple mechanisms of action, demonstrating cytotoxic activity against a range of cancer cell lines including leukemia, breast adenocarcinoma, neuroblastoma, and glioblastoma. It is widely used in cancer research for in vitro studies and has been investigated in vivo for its antitumor efficacy and DNA intercalation properties.

Research Area

Molecular Biology

Images & Validation

Key Properties

CAS Number519-23-3
MW246.31
Purity97.26% (May vary between batches)
FormulaC17H14N2
SMILESCc1c2[nH]c3ccccc3c2c(C)c2cnccc12
TargetTopoisomerase
SolubilityDMSO:5 mg/mL (20.3 mM)

Bioactivity

Target IC50
UKF-NB-3 cells:0.44±0.03μM |MCF-7 cells:1.25±0.13μM|IMR-32 cells:0.27±0.02μM|U-87MG cells (Glioblastoma):1.48±0.62 μM |HL-60 cells (leukemia):0.67±0.06μM|UKF-NB-4 cells:0.49±0.04μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NSC 71795, inhibit, Inhibitor, NSC71795, NSC-71795, Ellipticine, Elliptisine, Topoisomerase, Topo II

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 120.00
25 mg
$ 160.00
50 mg
$ 220.00
100 mg
$ 310.00
500 mg
$ 690.00
DispatchUsually dispatched within 5-10 working days
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