Eleven-Nineteen-Leukemia Protein IN-1

SKU: orb1745137

Description

The small molecule inhibitor Eleven-Nineteen-Leukemia Protein IN-1 potently targets the ENL YEATS domain with an IC50 of 14.5 nM. Its binding stabilizes the ENL protein in vitro, making it a valuable chemical probe for studying transcriptional regulation in acute leukemia and related epigenetic research fields.

Research Area

Cancer Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 2894121-68-5
• MW: 487.6
• Formula: C₂₇H₃₃N₇O₂
• SMILES: C[C@H]1CCCN1CC1=NC2=CC(NC(=O)C3=CC4=C(C=C3)N(CCN3CCOCC3)N=C4)=CC=C2N1
• Target: Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166642578