Elacestrant S enantiomer dihydrochloride

SKU: orb1709779

Description

Elacestrant (RAD1901) dihydrochloride is an orally bioavailable selective estrogen receptor degrader (SERD) with greater potency for ERα (IC50=48 nM) than ERβ. Its (S)-enantiomer is a low-activity form. This compound is used in research targeting hormone receptor-positive breast cancer, with applications in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• MW: 531.56
• Formula: C₃₀H₄₀Cl₂N₂O₂
• SMILES: OC1=CC=C2C[C@@H](C3=CC=C(OC)C=C3N(CC)CC4=CC=C(CCNCC)C=C4)CCC2=C1.[H]Cl.[H]Cl
• Target: Others,Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

127020970