eIF4E-IN-4

SKU: orb3028753

Description

eIF4E-IN-4 (Compound 33) is a selective inhibitor of the eukaryotic initiation factor 4E (eIF4E) with a biochemical activity value of 95 nM. It inhibits cap-dependent mRNA translation with an IC50 of 2.5 μM and is applicable in research on breast cancer, colon cancer, and head and neck cancer.

Research Area

Cell Biology

Key Properties

• CAS Number: 1373822-39-9
• MW: 475.822
• Formula: C₂₀H₁₉ClN₅O₅P
• SMILES: O=C1N=C(NC=2N=C(C=3C=CC(=CC3)P(=O)(O)O)N(C12)CCOC4=CC=C(Cl)C=C4)NC
• Target: PERK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PERK