EGTA-AM

SKU: orb1707971

Description

EGTA-AM is a cell-permeable calcium chelator used to study calcium signaling in cellular and physiological processes. Its role as a metabolic biomarker is investigated in research on the pathophysiology of both early- and late-onset preeclampsia.

Key Properties

• CAS Number: 99590-86-0
• MW: 668.6
• Purity: 97.45% (May vary between batches)
• Formula: C₂₆H₄₀N₂O₁₈
• SMILES: CC(=O)OCOC(=O)CN(CCOCCOCCN(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O
• Target: Others
• Solubility: DMSO:10 mg/mL (14.96 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (1.5 mM)

Bioactivity

• In Vitro:
  Many spontaneous but stimulus-dependent EPSCs are observed after the stimulus and are blocked by DNQX and reduced by EGTA-AM (50 μM).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EGTA Acetoxymethyl ester, EGTA AM, EGTAAM, EGTA-AM

Compound Identifiers

PubChem CID

121907