EGFR/VEGFR2-IN-4

SKU: orb2814622

Description

EGFR/VEGFR2-IN-4 (Compound 19) is a dual-targeting, irreversible inhibitor active against EGFR (IC50=18.7 nM) and VEGFR2 (IC50=102.3 nM) at 1 µM ATP. This small molecule is a valuable chemical probe for oncology research, facilitating the study of EGFR and VEGFR2 signaling pathways in both cellular and animal models of cancer.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 870962-74-6
• MW: 527.57
• Formula: C₂₉H₂₉N₅O₅
• SMILES: N(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C)C)=O)=C2)N=CN1)C=3C(=O)C=C(OCC4=CC=CC=C4)C(=O)C3
• Target: VEGFR,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44428890