EGFR/HDAC-IN-1

SKU: orb3027533

Description

EGFR/HDAC-IN-1 (Compound 22c2) is a potent dual inhibitor of epidermal growth factor receptor (EGFR) and histone deacetylase (HDAC), exhibiting IC50 values of 4.81 nM for EGFR, 119.4 nM for HDAC1, and 354.8 nM for HDAC3. It disrupts the EGFR signaling pathway and alters histone acetylation status, thereby inhibiting tumor cell proliferation. EGFR/HDAC-IN-1 is a promising candidate for research in non-small cell lung cancer (NSCLC).

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Epigenetics & Chromatin; Cell Biology, Molecular Biology, Signal Transduction

Key Properties

• Formula: C₂₂H₂₃ClN₄O₅
• Target: EGFR,HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR,HDAC